COLIGEN VET

Colistin Sulphate: 3000000 IU

Composition:
Each 1 ml contains
Colistin Sulphate: 3000000 IU

Indication:
Treatments of gastroenteritis, diarrhea in poultry, cattle as E.Coli, paratyphoid, necrotic enteritis diarrhea in piglets, digestive tract inflammation.
 
Description:
Colistin is an antibiotic from the group of polymyxins with bactericidal action against Gram negative bacteria like E. coli, Haemophilus and Salmonella spp. Polymyxins interact strongly with phospholipids and penetrate into and disrupt the structure of cell membranes. They disorganise the outer membrane of Gram-negative bacteria by binding lipopolysaccharide (LPS, endotoxin) through direct interaction with the anionic lipid A region, thereby neutralising the endotoxin capacity of LPS. Colistin sulphate is poorly absorbed after oral administration, and serum concentrations are generally undetectable. In chickens, residues in serum were detectable for up to 6 hours after administration in the drinking water. Orally administered colistin is eliminated almost totally in faeces.

Dosage: For oral administration.
Calves, goats and sheep: Twice daily 1 ml per 40 kg body weight for 5-7 days.
Poultry and swine: 1 liter per 2000 – 4000 liters of drinking water for 5-7 days.

Side effects:

Digestive alterations may appear, such as intestinal dysbiosis, accumulation of gases or mild diarrhea. Overdoses may result in renal failure.

Storages: Store in a dry & dark place.

Pack Size: 500 ml & 1000 ml